BARTFELD LAB
LANGE NACH DER WISSENSCHAFTEN
June 2025
Long Night of Sciences is always big fun. We talked about the new science building Der Simulierte Mensch (Si-M), Organ-on-a-chip technology, organoid culture, cell sorting with hands on experiments and live chip demonstration. This year it was at the TU main building but who knows maybe next time we can do it at the Si-M?! Already sparking ideas on what to show and do... :)
TALKING ABOUT ORGANOIDS
May 2025
It was an honor to give a lecture at the Life Sciences Alfried Krupp Kolleg in Greifswald. It was particularly cool to visit the Friedrich Loeffler Institute at the island Riems, an impressive institute dedicated animal health with many groups working on zoonotic viruses - also on organoids of course. If they identify potential for new transmission to human, it makes a lot of sense to test animal and human organoids in parallel. Thank you to Prof. Anca Dorhoi and Dr. Björn Corleis for inviting me!
PANEL DISCUSSION
May 2025
In this session, Sina Bartfeld, Co-Speaker of the building "Der Simulierte Mensch", Petra Reinke, Founding Director of the Berlin Center for Advanced Therapies (BeCAT), Philipp Landgraf, Co-Director of the Berlin Simulation & Training Center (BeST) and Wolfgang Hohlfeld, Head of Business Development at the company Hybrick discussed how architecture and design can foster or inhibit scientific cooperation.
ART AND SCIENCE
April 2025
Postdoc Cristina Brischetto hosted this art workshop in Berlin exploring the intersection of science and art. Nature is not only amazing in its complexity, but also inspiringly beautiful :)
Girls & Boys Day
April 2025
"It was so cool to see so many exciting devices and to use them for cool things, and also to see how the people work together!" - To hear the excitement and see the blinking eyes of school kids is the best payment. We are happy and proud to have done a first test round for our TOP-GUT themed school visit. The kids learned about organs, organoids, the blood and the immune system, Organ-on-a-chip and 3D printing. Shall we do this again next year? :)
SUCCESSFUL DEFENSE
March 2025
Congratulations Mastura Neyazi to the successful PhD defense! It was an exciting journey. We are proud to have had you with us and wish you success in your postdoc with Vivek Thacker! With the thesis committee members Thomas Dandekar, Marco Metzger, and Thomas Rudel.
CULTURING PLASMA CELLS
January 2025
Plasma cells are cells of the immune system that produce antibodies. In a living body, they can survive months, years or even a life-time. However, in the lab, they were difficult to culture long-term. PhD student Zehra Uyar-Aydin now published her work enabling long-term culture of human plasma cells. Congratulations Zehra!
TAGESSPIEGEL
November 2024
Karnkheiten heilen, an denen Millionen von Menschen leiden: Den Weg zu diesem Ziel bahnen diese ausgezeichneten Forschenden. Sie entwickeln dafür neue Methoden, von Mini-Organen bis hin zu "getarnten" Zellen. "Die 100 wichtigsten Köpfe der Berliner Wissenschaft" ist eine neue Serie vom Tagesspiegel - Sina Bartfeld ist auch dabei.
PostDocDay
November 2024
Postdoc Cristina Brischetto co-organized the Berlin PostDoc Day 2024. This day is an annual networking event organized by postdocs for postdocs and PhD students. Sina Bartfeld gave one of the talks, sharing the work of the group, but also some stories of her personal career path.
MENTORING
September 2024
The German Stem Cell Network (GSCN) magazine highlights the mentoring program, in which Sina Bartfeld is a mentor. She says: „I enjoy being a mentor for three reasons. First, it is simply fantastic to be able to help. Second, the reflection makes me learn and grow as well, knowing the problems, maybe I can contribute better to improving the system. Third, it is payback to my mentors – without them I would not be where I am.
STAMMZELLNETZWERK
September 2024
Sina Bartfeld wurde als designierte Präsidentin in den Vorstand des German Stem Cell Networks berufen. Das German Stem Cell Network (GSCN) fördert die Stammzellenforschung in Deutschland. Sechs Jahre wird Prof. Dr. Sina Bartfeld nun die wichtigste Vereinigung der Stammzellwissenschaftler in Deutschland im Vorstand unterstützen, davon zwei Jahre als designierte Präsidentin, zwei Jahre als Präsidentin und zwei Jahre als Senior Präsidentin.
Copyright: GSCN / Arne Sattler
OPEN SCIENCE AMBASSADOR
September 2024
Postdoc Cristina Brischetto was given the ambassadorship to implement the open science activities for the Faculty III of the Technische Universität Berlin. Until July 2025 Cristina will work together with the other ambassadors to improve our activities in the Open Science field. Go Cristina!
Si-Mposium 2024
September 2024
Although the Si-M (der Simulierte Mensch) is not yet open, we already get together as a community: Every year, the Si-Mposium is organized, an event to foster exchange amongst engineers, medical professionals and scientists. Milica Radisic (University of Toronto) and Lauriane Cabon (Roche, Basel) gave inspiring keynotes. Looking forward to see you next year!
PANEL DISCUSSION
September 2024
Mithilfe von Stammzellen lassen sich zukünftig neue Therapien entwickeln: Man kann aus ihnen kleine Gewebestückchen und Organoide züchten und an diesen Medikamente auf ihre Wirkung testen oder sie als Ersatz für verloren gegangenes Gewebe verwenden. In der vom German Stem Cell Network organisierten Diskussion dreht es sich um Stand und Zukunft der Stammzellforschung sowie neue Behandlungsmöglichkeiten.
Copyright: GSCN / Arne Sattler
DGHM MEETING IN WÜRZBURG
June 2024
The German Society for Hygiene and Microbiology (DGHM) had the major conference together with the VAAM in Würzburg to discuss the latest findings on infectious disease. So many scientific friends were there, the Infect-Net, GRK2157 and CRC Decide, such an amazing community! Sina Bartfeld as deputy chair of the group "Gastrointestinal Infections" of the DGHM co-organized and chaired one session. Save the date: 22.-24. September 2025 in Jena.
TOP-GUT
May 2024
We had the Kick-Off meeting for "TOP-GUT", a new EU HORIZON MSCA Doctoral Network, in Berlin. It was amazing to see everybody and talk about the plans. We also heard fantastic keynote lectures from Stefan Krauss and Thomas Steger-Hartmann. The network provides training on organoids to model physiology and pathology of the gastrointestinal tract. Sina Bartfeld is coordinator of the network.
NEW PAPER OUT
April 2024
In this paper, we show that SARS-CoV-2 can infect intestinal, but not gastric organoids. The main entry receptor of the virus, ACE2, is differentially expressed in the different segments of the adult gastrointestinal tract and the differential expression pattern of ACE2 regulates SARS-CoV-2 infection. This was a collaborative effort between many groups, especially colleagues from the Charite Berlin, and it was the main work of PhD student Mindaugas Pauzuolis.
UNI STEM DAY
March 2024
Every year, the German Stem Cell Network organizes a full day of stem cell education for biology-loving high-school kids. Sina Bartfeld contributed now for the 4th year and gave a talk about adult stem cells and organoids. Check out the GSCN website to save the date for next year.
GEN- UND ZELLTHERAPIEN
März 2024
In den ersten drei Monaten schon über 30.000 Mal aufgerufen worden: Ein Buch mit Übersichtsartikeln zu Forschung, klinischer Anwendung und Gesellschaft. Das Buch kann kostenlos bei der AG Gentechnologiebericht als PDF runtergeladen werden. Das gedruckte Buch kann beim Springer Verlag gekauft werden. Sina Bartfeld ist Mitglied der AG Gentechnologiebericht und Mitherausgeberin des Buches. Das Buch ist Ende Dezember 2023 erschienen.
SUCCESSFUL DEFENSE
January 2024: Congratulations Mindaugas Pauzuolis to the successful defense! Together with Carmen Aguilar, Emmanuel Saliba and many collaborators, Mindi has driven the identification of gastric pit cells as target cells of Helicobacter pylori (published) and he is finalizing another story on SARS-CoV-2 infection in the stomach. Well done Mindi! With the committee: Emmanuell Saliba, Redmond Smyth and Christine Krempl.
PODIUMSDISKUSSION
Dezember 2023: Aktuelle Themen der Gen- und Zelltherapie diskutierte Sina Bartfeld mit Boris Fehse, Martin Zenke, Dieter Birnbacher und Hildegard Büning auf der Abendveranstaltung der Arbeitsgruppe Gentechnologiebericht, gefördert vom BIH at Charite. Die Wissenschaftsjounalistin Christina Berndt moderierte des Abend. Ein Videomitschnitt wird auf der Website der AG bereit gestellt werden. Sina Bartfeld ist Mitglied der AG.
COURSE ON STEM CELL BIOLOGY
September 2023
The ISSCR partners with the São Paulo Research Foundation and the Federal University of São Paulo to deliver a Stem Cell Biology Course. The course follows the concept from the ISSCR education committee (scroll down for more info). We are proud to accompany this endeavour - and we think it would be cool to have a Stem Cell Biology Course at every university! TU Berlin will follow.
LABORJOURNAL
April 2023
Das Magazin "Laborjournal" hat eine Titelgeschichte über intelligente Modellorgane veröffentlicht. Mit dabei sind auch unsere Organoide aus adulten Stammzellen, die Organ-on-a-Chip Technologie und die Vision des Simulierten Menschen.
Der Artikel beginnt auf Seite 46, das PDF ist frei erhältlich beim Laborjournal.
UNISTEMDAY 2023
March 2023
An amazing opportunity for high school students to hear about stem cell science - 300 high school students and their teachers came to the UniStemDay 2023. Amongst others, Sina Bartfeld gave a lecture on organoids, and students visited several labs afterwards. Save the date for next year: 24.3.2024 at MDC Berlin! The UniStemDay is an annual event organized by the German Stem Cell Network GSCN.
CORE CONCEPTS IN STEM CELL BIOLOGY
A learning guide
The Education Committee of the International Society for Stem Cell Research (ISSCR) has prepared a syllabus and learning guide to aid instructors in preparing a course on the “Introduction to Stem Cell Biology.” The materials are intended for teaching undergraduate students, early graduate students, or medical students who are interested in stem cell biology. Sina Bartfeld is part of the ISSCR education committee.
My students asked me to provide a crash course on scientific writing (how to write your final thesis, how to write a paper?). This here is the youtube version to conserve it for the future. Hope it helps!
ORGANOIDE
Ihre Bedeutung für Forschung, Medizin und Gesellschaft
Ein Buch mit fachlichen Übersichtsartikeln, einem Interview mit Hans Clevers, und weiteren Beiträgen zur Einschätzung und gesellschaftlichen Bedeutung der Technologie.
Erschienen in der Reihe ‚Forschungsberichte der interdisziplinären Arbeitsgruppen derBerlin-Brandenburgischen Akademie der Wissenschaften’. Sina Bartfeld ist Mitglied der Arbeitsgruppe und Mit-Herausgeberin des Buches.
LIFE SCIENCE REPORT
January 2023
The Life Science Report 2022/2023 puts a spotlight on the new science building "Der Simulierte Mensch" in Berlin, which will house researchers of the Charite Berlin and the Technical University Berlin side by side to develop in vitro models for human disease. They also highlight our work on organoids (Page 17 - page 20).
DIE GROSSE BESCHLEUNIGUNG
November 2022 Podcast
Die Weltbevölkerung wächst immer schneller, Technologie wird leistungsfähiger und das globale Klima erwärmt sich weiter und weiter. Gefühlt wird alles immer schneller. Der Journalist Christian Stöcker hilft im Gespräch mit Expertinnen und Experten, die Große Beschleunigung besser zu begreifen. In diesem Teil spricht er mit Sina Bartfeld über Organoide, personalisierte Medizin und Avatare für Patienten.
TIERVERSUCHE -
IMMER NOCH UNVERZICHTBAR?
BR RADIOWISSEN Podcast 21.10.2021
Tierversuche sind ein Grundpfeiler medizinischer Forschung, Labore die Lebenswelt zahlreicher Tierarten. Als Gesellschaft akzeptieren wir diese Tiernutzung, auch wenn sich dagegen immer wieder Proteste regen. Wie wird dem Wohlergehen dieser Tiere Rechnung getragen? Und gibt es vielleicht doch Alternativen?
Vortrag Sina Bartfeld UniStemDay 2021
ORGANOIDS -
from stem cells to future technologies
The report on organoids by the German Stem Cell Network (GSCN) offers a tour of the latest developments in this major research field and of current and potential future applications. The focus is on current organoid research projects and companies, with viewpoints from a range of researchers and stakeholders.
This is followed by the IAG’s core statements and recommendations for action on the use of organoids.
NETZWERK
Juli 2022
Das Bundesministerium für Bildung und Forschung (BMBF) fördert in den nächsten drei Jahren den Aufbau eines Netzwerks von Infektionsforscherinnen in Deutschland. RWTH-Professorin Gabriele Pradel leitet das Projekt. Zum Gründungsteam gehören die Kolleginnen Melanie Brinkmann (TU Braunschweig), Petra Dersch (Universität Münster), Sandra Ciesek (Universitätsklinikum Frankfurt), Cynthia Sharma (Universität Würzburg) und Sina Bartfeld (TU Berlin).
PRIZE FOR PHD ACHIEVEMENTS
We proudly congratulate Mindaugas Pauzuolis who received the prize of the workgroup Gastrointestinal Infections of the German Society for Hygiene and Microbiology (DGHM) for his outstanding scientific achievements!
PRIZE FOR PRESENTATION
We proudly congratulate Zehra Uyar-Aydin, who has received the first prize for her presentation about long-lived plasma cells at TERMIS conference 2022 in Krakow!
PHD THESIS
We congratulate Kübrah Gürcan for the successful defense of her thesis!
